The 2nd French “3R” Days 2026 were held online on July 2, 2026. The event brochure is available, and recordings of the presentations will be available soon.
The first French “3R” conference, November 21–22, 2024, at the National Veterinary School of Alfort: These events focused on three main themes: the implementation of 3R-sharing tools, substitution, and digital approaches.
Following on from the actions undertaken by the FC3R over the last two years, the first French 3R Days aimed to promote the 3R principle (Replace, Reduce, Refine) in France. This symposium encouraged interaction between researchers, institutions and civil society players, while promoting the exchange of knowledge and best practices around the 3Rs and highlighting the significant advances made in France in this field.
The program was structured around four thematic sessions, covering FC3R actions, current initiatives and prospects for further integrating the 3Rs principle into scientific practice.
Finally, the FC3R Scientific Committee presented its first 3R Awards for “Research” and “Culture of Care”, in recognition of innovative and significant initiatives to implement the 3R principle in France.
Replays of most of the speeches are available on the event page.
Of particular note is the overview of FC3R’s activities during these events:

Athanassia SOTIROPOULOS
Inserm Research Director, Director of GIS FC3R
Report on the Work of the FC3R Advisory and Reflection Council – Working Group: Education

Valérie LEMARCHANDEL
Scientific Director, Fondation pour la Recherche Médicale (FRM)
Member, FC3R Conseil d’Orientation et de Réflexion (COR)
Report on the Work of the FC3R Steering and Reflection Council – Working Group: Severity

Roland CASH
Vice-president of Transcience, physician, health economics consultant.
Member of the FC3R Conseil d’Orientation et de Réflexion (COR).
Human Brain Organoids for the Study of Bipolar Disorders

Stéphane JAMAIN
Researcher, Head of Genomics Group, Institut Mondor de Recherche Biomédicale – Créteil, France
A simple method for generating 3D muscle fibers in vitro

Bruno CADOT
Researcher, Institute of Myology – Inserm U974
Development of a Non-Pathological 3D Breast Model Using Bioprinting

Antonella RAFFO ROMERO
Postdoctoral fellow in the PRISM laboratory (Proteomics Inflammatory Response Mass Spectrometry) – Inserm U1192, Lille
Digital Twins to Predict Fetal Exposure to Medications: The Case of Antidepressants

Laure-Hélène PRETA
Pharmacist at URP 7323 Pharmacology and evaluation of therapeutics in children and pregnant women – Université Paris Cité



